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Early research in patients already taking an antidepressant shows that taking crocin, a chemical found in saffron, for 4 weeks reduces symptoms of depression more than taking the antidepressant alone. An evaluation of the effects of saffron supplementation on the asthma clinical symptoms and asthma severity in patients with mild and moderate persistent allergic asthma: a double-blind, randomized placebo-controlled trial. View abstract. Kubo I, Kinst-Hori I. Flavonols from saffron flower: tyrosinase inhibitory activity and inhibition mechanism. Kanakis, C. D., Daferera, D. J., Tarantilis, P. A., and Polissiou, M. G. Qualitative determination of volatile compounds and quantitative evaluation of safranal and 4-hydroxy-2,6,6-trimethyl-1-cyclohexene-1-carboxaldehyde (HTCC) in Greek saffron. 2006;287(1-2):127-135. A., Atienzar, M., and Garcia-Olmo, D. Effects of long-term treatment of colon adenocarcinoma with crocin, a carotenoid from saffron (Crocus sativus L.): an experimental study in the rat. The efficacy of saffron in the treatment of mild to moderate depression: A meta-analysis. . Akhondzadeh S, Tahmacebi-Pour N, Noorbala AA, et al. Ferrence, S. C. and Bendersky, G. Therapy with saffron and the goddess at Thera. Pharmacopsychiatry. Zhongguo Zhong.Yao Za Zhi. Boskabady, M. H., Shafei, M. N., Shakiba, A., and Sefidi, H. S. Effect of aqueous-ethanol extract from Crocus sativus (saffron) on guinea-pig isolated heart. Harvesting. Some research shows the taking a specific product containing saffron, anise, and celery seed reduces pain during the menstrual cycle. Some studies show that saffron might be as effective as taking a prescription antidepressant, such as fluoxetine, imipramine, or citalopram. Pharmacopsychiatry. View abstract. The term "autumn crocus" is also used for species in the Colchicum genus, which strongly resemble crocuses. The spice Saffron. Without it, an Indian curry or Spanish paella just wouldn’t be the same. It is a highly prized spice used for both sweet and savory dishes, most notably Italian risotto, Spanish paella, and many Iranian and Asian recipes. View abstract. 2008;11(3):1-14. TRILLIUM- calendula officinalis, chamomilla, crocus sativus, equisetum arvense, hamamelis virginiana, lamium album, millefolium, plantago major, quercus robur, thlaspi bursa-pastoris, trillium pendulum, urtica dioica, viscum album liquid Number of versions: 3. 2003;12(4):474-476. You can collect the stigmas to produce your own saffron, but be aware that it takes at least 150 to 200 flowers to produce around just one gram of this spice. The median lethal doses (LD50) of C. sativus are 200 mg/ml and 20.7 g/kg in vitro and in animal studie … Hosseinzadeh, H., Abootorabi, A., and Sadeghnia, H. R. Protective effect of Crocus sativus stigma extract and crocin (trans-crocin 4) on methyl methanesulfonate-induced DNA damage in mice organs. Medically reviewed by Drugs.com. Safarinejad MR, Shafiei N, Safarinejad S. A prospective double-blind randomized placebo-controlled study of the effect of saffron (Crocus sativus Linn.) This salt combination may also be used for purposes not listed in this medication guide. View abstract. Planta 2004;219(6):955-966. Phytomedicine. View abstract. 2007;157(13-14):315-319. The effect of saffron, Crocus sativus stigma, extract and its constituents, safranal and crocin on sexual behaviors in normal male rats. Crocus sativus, commonly known as saffron crocus, or autu… Join the Homeopathy Plus Newsletter J. View abstract. Description. J Cardiovasc.Pharmacol 2006;47(1):70-76. Akhondzadeh Basti A, Moshiri E, Noorbala AA, et al. Saffron, Crocus sativus, is the source of a rare spice valued as a food flavouring and colouring. Crocus sativus L. in the treatment of mild to moderate depression: a double-blind, randomized and placebo-controlled trial. A group of eye disorders that can lead to vision loss (glaucoma). Last updated on Jan 20, 2020. C. sativus is a perennial herb cultivated in several countries of mild and dry climate, such as Iran, India, Greece, Morocco, Spain, Italy, Turkey, Pakistan, Azerbaijan, China, and Egypt. View abstract. Imenshahidi, M., Hosseinzadeh, H., and Javadpour, Y. Hypotensive effect of aqueous saffron extract (Crocus sativus L.) and its constituents, safranal and crocin, in normotensive and hypertensive rats. J Nat.Prod. Dutch yellow crocus (C. flavus), from stony slopes in southeastern Europe, is another popular spring species, as is C. biflorus, tinged purple and with yellow throat,… View abstract. J Agric.Food Chem. Some research shows that saffron might improve sperm function in men. In texts of Ayurveda the herb Crocus Sativus or kumkuma or saffron is grouped under “Varnya” gana. View abstract. Phytother.Res 2010;24(3):410-413. Crocus sieberi Sieber's crocus Crocus tommasinianus woodland crocus Crocus vernus dutch crocus Legal Status. Title The Herb Book. Native Introduced ... Crocus imperati early crocus Crocus sativus . Zilaee M, Hosseini SA, Jafarirad S, et al. Home; Classification; Adaptation/ Habitat; Medical Uses; Nutrition; Reproduction; Interactions; Fun Facts; Recipes ; References; Contact Me; Medical Uses: Useful from Past to Present. Homeopathic Crocus Sativus indications, uses & symptoms from 12 cross linked materia medicas. 2004;47(2):199-226. Antiabsence effects of safranal in acute experimental seizure models: EEG and autoradiography. Antitumor activity of Saffron (Crocus sativus). J Affect Disord. 2016 Sep 5. 1998;52(5):205-207. Brown AC, Hairfield M, Richards DG, et al. View abstract. Buy Crocus sativus, Kesar, Saffron - Bulbs (set of 5) and 6000+ more gardening products online. View abstract. Miller TL, Willett SL, Moss ME, et al. View abstract. The species is hermaphrodite (has both male and female organs) and is pollinated by Bees, butterflies. Indian J Med.Sci. The search terms used were saffron, Crocus sativus, crocin, crocetin, safranal, picrocrocin, Avicenna and ‘Ibn Sina’. Giaccio M. Crocetin from saffron: an active component of an ancient spice. Safarinejad MR, Shafiei N, Safarinejad S. An open label, randomized, fixed-dose, crossover study comparing efficacy and safety of sildenafil citrate and saffron (Crocus sativus Linn.) Sadeghnia, H. R., Cortez, M. A., Liu, D., Hosseinzadeh, H., and Snead, O. C., III. Available 2C-30C, 200C, 4X-30X, 30C, 200CH, 1M-10M, Q Modaghegh, M. H., Shahabian, M., Esmaeili, H. A., Rajbai, O., and Hosseinzadeh, H. Safety evaluation of saffron (Crocus sativus) tablets in healthy volunteers. View abstract. Early research shows that taking saffron, or a chemical from saffron called crocetin, can decrease fatigue and improve muscle strength in men during exercise. 2005;81(4):805-813. Saffron or Crocus sativus L. (C. sativus) has been widely used as a medicinal plant to promote human health, especially in Asia. Food Chem Toxicol. 2010 Jul-Aug;22(4):240-50. 2008;15(6-7):491-495. Pharmacopsychiatry. Zhou, S. D. and Zhong, H. J. HPLC determination of crocin-I, crocin-II and crocins in Crocus sativus extract and tablets. The flower styles are commonly used as a flavouring and yellow colouring for various foods such as bread, soups, sauces, rice and puddings [2, 4, 7, 14, 21, 27, 34, 183]. The high labor costs associated with the spice have resulted in a limited supply. Premenstrual syndrome (PMS). 2002;65(10):1452-1456. Xi, L., Qian, Z., Xu, G., Zheng, S., Sun, S., Wen, N., Sheng, L., Shi, Y., and Zhang, Y. View abstract. - 0 ft. 4 in. Karcom. View abstract. View abstract. Perspect.Biol.Med. WebMD does not provide medical advice, diagnosis or treatment. The alpine species, C. vernus, is the chief ancestor of the common garden crocus. Azimi P, Ghiasvand R Feizi A, Hariri M, Abbasi B. Publisher Bantam books Year 1983 ISBN 0-553-23827-2 Description Lots of information tightly crammed into a fairly small book. View abstract. Early research shows that taking saffron might prevent sore muscles in men who do not typically exercise. Experientia 1975;31:548-9. Taking a specific saffron extract by mouth for up to 22 weeks seems to improve symptoms of Alzheimer's disease. View abstract. Crocus orsinii Parl. Noorbala AA, Akhondzadeh S, Tahmacebi-Pour N, Jamshidi AH. on semen parameters and seminal plasma antioxidant capacity in infertile men with idiopathic oligoasthenoteratozoospermia. The Use of Crocetin in Experimental Atherosclerosis. 2016 Jun 1;13(2):195-9. Crocus sativus Linn (Iridaceae) is used widely in tropical and subtropical countries for a variety of purposes in both household and for medicinal purposes. Crocus sativus is a CORM growing to 0.1 m (0ft 4in) by 0.1 m (0ft 4in). The Latin name of this herb is Crocus sativus. Title 21. The main components of saffron are crocin, picrocrocin and safranal. Saffron is a species of crocus that is grown for its prized stamens. Allergy 1997;52:633-41. Effects of Crocus sativus petals' extract on rat blood pressure and on responses induced by electrical field stimulation in the rat isolated vas deferens and guinea-pig ileum. But other research shows that taking saffron by mouth is not beneficial. View abstract. 2012 Oct;223(4):381-8. 2004;5(1):70-76. Hosseinzadeh, H. and Noraei, N. B. Anxiolytic and hypnotic effect of Crocus sativus aqueous extract and its constituents, crocin and safranal, in mice. Growing and Harvesting Saffron Crocus Sativus . Saffron crocus may have first appeared in Greece as a sterile triploid … Gregory, M. J., Menary, R. C., and Davies, N. W. Effect of drying temperature and air flow on the production and retention of secondary metabolites in saffron. View abstract. 5-18-2005;53(10):3974-3979. An eye disease that leads to vision loss in older adults (age-related macular degeneration or AMD). Species. Sarris, J. Herbal medicines in the treatment of psychiatric disorders: a systematic review. Rev Diabet Stud. 2017 Jan 1;207:188-196. doi: 10.1016/j.jad.2016.09.047. 2017 Jul;50(4):152-160. doi: 10.1055/s-0042-116159. Colchicine is listed as a substrate of CYP3A4 (cytochrome P450) hepatic … Phytother Res. Mol.Cell Biochem. Datasheet. Crocus sativus plant morphology: (A) saffron plant; (B) types of roots in saffron; (C) saffron leaves; (D) saffron flower. View abstract. Effects of a Topical Saffron (Crocus sativus L) Gel on Erectile Dysfunction in Diabetics: A Randomized, Parallel-Group, Double-Blind, Placebo-Controlled Trial. A very distinctive aroma. Sign Up to Receive Our Free Coroanvirus Newsletter, Recovering From Trauma: 13 Tips to Help You Heal, MS and Depression: Tips for Mental Fitness, Antidepressant-induced sexual dysfunction, Antipsychotic-induced metabolic side effects. June 6, 2017 Saffron is the dried stigma of a flowering plant Crocus sativus and is considered the most expensive spice in the world. Electronic Code of Federal Regulations. Wetland Status . Pitsikas, N., Boultadakis, A., Georgiadou, G., Tarantilis, P. A., and Sakellaridis, N. Effects of the active constituents of Crocus sativus L., crocins, in an animal model of anxiety. Saffron might work about as well as the prescription drug donepezil (Aricept). J Complement Integr Med. View abstract. It is a bulbous perennial plant that belongs to the family of Iridaceae, in the genus, Crocus, and known botanically as Crocus sativus. 5-1-2009;12(9):690-695. View abstract. BMC Complement Altern Med 2004;4:12. Crocin, the main active saffron constituent, as an adjunctive treatment in major depressive disorder: a randomized, double-blind, placebo-controlled, pilot clinical trial. Saffron has long been used in cooking and it is also a powerful medicinal herb when used in the right amounts. View abstract. Saffron is a native of the Middle East and prefers good sandy loam in a protected, sunny position. Asdaq, S. M. and Inamdar, M. N. Potential of Crocus sativus (saffron) and its constituent, crocin, as hypolipidemic and antioxidant in rats. Introduction. View abstract. View abstract. Saffron or Crocus sativus L. (C. sativus) has been widely used as a medicinal plant to promote human health, especially in Asia. Phytomedicine. View abstract. View abstract. Preventive effects of 10-day supplementation with saffron and indomethacin on the delayed-onset muscle soreness. J Ethnopharmacol. However, taking saffron might not help for all types of depression. Crocus Sativus. View abstract. View abstract. Saffron is one of the oldest spices, its history going back to the highest antiquity. Tarantilis, P. A., Morjani, H., Polissiou, M., and Manfait, M. Inhibition of growth and induction of differentiation of promyelocytic leukemia (HL-60) by carotenoids from Crocus sativus L. Anticancer Res 1994;14(5A):1913-1918. View abstract. View abstract. View abstract. Abe, K., Sugiura, M., Shoyama, Y., and Saito, H. Crocin antagonizes ethanol inhibition of NMDA receptor-mediated responses in rat hippocampal neurons. View abstract. One of the traditional spices used in Arab-Islamic medicines is saffron (Crocus sativus). C. sativus is a perennial herb cultivated in several countries of mild and dry climate, such as Iran, India, Greece, Morocco, Spain, Italy, Turkey, Pakistan, Azerbaijan, China, and Egypt. View abstract. Taking an antidepressant can make some people lose interest in sex. View abstract. Ahmad, A. S., Ansari, M. A., Ahmad, M., Saleem, S., Yousuf, S., Hoda, M. N., and Islam, F. Neuroprotection by crocetin in a hemi-parkinsonian rat model. 2007;29(3):175-180. There are simply too many possible applications of saffron as a medicinal plant. Phytother Res. 2015 Oct;20(4):283-6. 2009;8(2):315-323. Quiz: What Do You Know About Vitamin B12 Deficiency? Characterization of the platelet aggregation inducer and inhibitor isolated from Crocus sativus. Taking saffron doesn't seem to reduce lipid levels in most people. The following doses have been studied in scientific research: Planta Med. Occupational allergy in saffron workers. View abstract. Liu, T. Z. and Qian, Z. Y. Do not use more than prescribed dose. [Study of the effect of crocin on rat experimental hyperlipemia and the underlying mechanisms]. View abstract. Nutr Res 2009;29:145-50. The Saffron Crocus (Crocus sativus) is a surprisingly easy-to-grow flower that adds a splash of color in the fall, when this plant blooms. View abstract. View abstract. Recent research has examined saffron’s antidepressant properties. View abstract. View abstract. Zhao, P., Luo, C. L., Wu, X. H., Hu, H. B., Lv, C. F., and Ji, H. Y. Most of these effects have been studied in modern pharmacology and are well documented. 2017 Aug;33:58-64. doi: 10.1016/j.ctim.2017.06.001. Exp.Oncol. Early research shows that taking saffron might reduce some symptoms of asthma in people with allergic asthma. Hausenblas HA, Saha D, Dubyak PJ, Anton SD. Cancer chemopreventive and tumoricidal properties of saffron (Crocus sativus L.). Early research shows that taking saffron for 4 weeks improves satisfaction with sex in men and women taking an antidepressant. View abstract. They are an essential ingredient of many traditional dishes such as paella, bouillabaisse, risotto milanese and various other Italian dishes. By Dr G. P. Singh Last updated May 6, 2020. Crocus - such a pretty flower but in homeopathic potencies helps symptoms of black and stringy haemorrhages, tingling, anger followed by quick remorse, laughing mania, and more. Magesh, V., Singh, J. P., Selvendiran, K., Ekambaram, G., and Sakthisekaran, D. Antitumour activity of crocetin in accordance to tumor incidence, antioxidant status, drug metabolizing enzymes and histopathological studies. 1993;8(4):339-343. Comparison of petal of Crocus sativus L. and fluoxetine in the treatment of depressed outpatients: a pilot double-blind randomized trial. It is harvested from the wild for local use as a food, medicine and source of materials. 1991;31(1):75-83. Maccarone, R., Di Marco, S., and Bisti, S. Saffron supplement maintains morphology and function after exposure to damaging light in mammalian retina. But all parts of the plant are considered toxic. Where did you or where do you plan to purchase this product? View abstract. Traditional and Modern Uses of Saffron ( Crocus Sativus) 1. Cancer Biother. 2008;13(5):1135-1147. View abstract. View abstract. But all parts of the plant are considered toxic. Behav.Brain Res 10-2-2006;173(1):112-115. Menstrual cramps (dysmenorrhea). 2007;14(4):256-262. 2008;27(12):657-664. A native of southern Europe and Asia, the saffron crocus is unique among the 75 other crocus species. Hosseini A, Razavi BM, Hosseinzadeh H. Pharmacokinetic properties of saffron and its active components. 537. Abdullaev FI. (Arabian) Zaffer. Role of caspases and Bax protein in saffron-induced apoptosis in MCF-7 cells. Avicenna described various uses of saffron, including its use as an antidepressant, hypnotic, anti-inflammatory, and others. Falsini B, Piccardi M, Minnella A, Savastano C, Capoluongo E, Fadda A, Balestrazzi E, Maccarone R, Bisti S. Influence of saffron supplementation on retinal flicker sensitivity in early age-related macular degeneration. 6-29-2005;94(26-27):1090. It is widely used as spice and as a coloring and flavoring agent in the preparation of various foods and cosmetics. Kell G, Rao A, Beccaria G, et al. View abstract. Identity Taxonomic Tree List of Pests Uses List Summary. If you liked the information on this page you may also enjoy our regular newsletter, full of information, news, discounts, and offers. Wien.Med.Wochenschr. Muscle soreness caused by exercise. Zheng, S., Qian, Z., Sheng, L., and Wen, N. Crocetin attenuates atherosclerosis in hyperlipidemic rabbits through inhibition of LDL oxidation. Symptoms of the mind Crocus sativus, commonly known as saffron crocus, or autumn crocus, is a species of flowering plant of the Crocus genus in the iris family Iridaceae. J Pharm Sci 1982;71:173-7. J Agric.Food Chem. Early research shows that applying saffron to the skin can improve symptoms of erectile dysfunction. Ma SP, Liu BL. J Integr Med. Ayatollahi H, Javan AO, Khajedaluee M, Shahroodian M, Hosseinzadeh H. Effect of Crocus sativus L. (saffron) on coagulation and anticoagulation systems in healthy volunteers. Crocus sativus is a Corm up to 0.10 metres tall. J Agric.Food Chem. Saffron, the dried stigma of the Crocus sativus flower, is considered among the main terroir products of Morocco. Early research shows that taking saffron for 4 weeks, in addition to regular treatment, might reduce some of the symptoms of glaucoma. View abstract. J Nutr.Biochem. Cultivation; Medicinal Action and Uses; Preparations---Synonyms---Crocus. View abstract. Tabeshpour J, Sobhani F, Sadjadi SA, et al. Saffron crocus Flowers showing crimson stigmas Scientific classification Kingdom: Plantae Clade: Tracheophytes Clade: Angiosperms Clade: Monocots Order: Asparagales Family: Iridaceae Genus: Crocus Species: C. sativus Binomial name Crocus sativus L. Synonyms Crocus autumnalis Sm. Kianbakht S, Ghazavi A. Immunomodulatory effects of saffron: a randomized double-blind placebo-controlled clinical trial. Heidary M, Vahhabi S, Reza Nejadi J, et al. In this study, the anxiolytic and hypnotic effects of saffron aqueous extract and its constituents, crocin and safranal, were studied in mice. Lopresti AL, Drummond PD. officinalis; Description. 2019;33(6):1648-1657. View abstract. View abstract. Psychopharmacology (Berl). (c) 1997-2019 Homeopathy Plus – Ph: +61 02 4304 0822 / email: office(at)homeopathyplus.com – 7B/1 Pioneer Avenue Tuggerah NSW 2259, View our privacy policy and disclaimer here. Saffron is a delicious and colorful seasoning that is used in breads, desserts, and main dishes in many parts of the world, from England to India, from the Middle East to Scandinavia, and all around the Mediterranean. Some research has also shown that taking saffron by mouth can benefit men with erectile dysfunction. Growing saffron in the home garden is not difficult given a sunny position and a well drained soil. View abstract. View abstract. Don't be expecting a bumper harvest! View abstract. View abstract. Akhondzadeh S, Fallah-Pour H, Afkham K, et al. View abstract. Latin name: Crocus sativus Family: Iridaceae (Iris Family) Medicinal use of Saffron: Saffron is a famous medicinal herb with a long history of effective use, though it is little used at present because cheaper and more effective herbs are available. © 2005 - 2019 WebMD LLC. Aung, H. H., Wang, C. Z., Ni, M., Fishbein, A., Mehendale, S. R., Xie, J. T., Shoyama, C. Y., and Yuan, C. S. Crocin from Crocus sativus possesses significant anti-proliferation effects on human colorectal cancer cells. View abstract. Li, C. Y. and Wu, T. S. Constituents of the stigmas of Crocus sativus and their tyrosinase inhibitory activity. Haqqaq EG, Abou-Moustafa MA, Boucher W, Theoharides TC. Don't be expecting a bumper harvest! Medical nutrition therapy as a potential complementary treatment for psoriasis - five case reports. Saffron is also used … In texts of Ayurveda the herb Crocus Sativus or kumkuma or saffron is grouped under “Varnya” gana. Pitsikas, N. and Sakellaridis, N. Crocus sativus L. extracts antagonize memory impairments in different behavioural tasks in the rat. View abstract. Saffron therapy for the treatment of mild/moderate age-related macular degeneration: a randomised clinical trial. Erectile dysfunction (ED). View abstract. Therefore, it is possible that saffron is an herb that can help with patients with the fatal disease of cancer to become better and hopefully take away some of the suffering. It is used extensively in European, North African, and Asian cuisines … View abstract. All rights reserved. View abstract. Saffron is one of the costliest spices used in Ayurveda, Unani and Chinese medicinal preparations. Phytomedicine. Early male orgasm (premature ejaculation). This survey is being conducted by the WebMD marketing sciences department. TRILLIUM- calendula officinalis, chamomilla, crocus sativus, equisetum arvense, hamamelis virginiana, lamium album, millefolium, plantago major, quercus robur, thlaspi bursa-pastoris, trillium pendulum, urtica dioica, viscum album liquid If this SPL contains inactivated NDCs listed by the FDA initiated compliance action, they will be specified as such. This medicine Crocus Sativus plays an important role in checking the secretion of blood because the color of blood turns black and there are multiple fibrous present in the blood. View abstract. View abstract. Safran officinarum Medik. Phytomedicine. Autumn crocus should be avoided in patients on colchicine because of the potential for additive adverse and therapeutic effects. Brain Res 3-16-1998;787(1):132-138. 2-7-2007;55(3):970-977. Abe, K. and Saito, H. Effects of saffron extract and its constituent crocin on learning behaviour and long-term potentiation. Women and their male partners planning pregnancy should avoid use of autumn crocus because of potential complications and limited data available for use in humans.32. Pharmacological studies of glycosides of saffron crocus (Crocus sativus): effects on blood coagulation, platelet aggregation, and thrombosis. Phytomedicine. Saffron (Crocus sativus) is the world’s most expensive spice. View abstract. Anxiety. There are simply too many possible applications of saffron as a medicinal plant. Complement Ther Med. Growing and Harvesting Saffron Crocus. DESCRIPTION. Iran Biomed.J 2008;12(2):93-100. Apart from its use in preparation of food, the stigmas of the plant are used for the treatment of a variety of disorders traditionally. 2006;47(7):3156-3163. Pharmacol Res. - 0 ft. 10 in. View abstract. High blood pressure. Home; Phytology; Saffron; Etymologie; Effect; Shop; Medical use of saffron. Hosseinzadeh, H. and Younesi, H. M. Antinociceptive and anti-inflammatory effects of Crocus sativus L. stigma and petal extracts in mice. BMC Complement Altern Med. It is hardy to zone (UK) 6 and is not frost tender. Crocus sativus is a very ancient medicinal plant, and since several Centuries has become a high quality spice plant. View abstract. [Saffron for the mood]. illeg. View abstract. Pak.J Biol.Sci. View abstract. Clinical evidence on the effects of saffron (Crocus sativus L.) on cardiovascular risk factors: A systematic review meta-analysis. Sorry, the comment form is closed at this time. Its formal name of Crocus sativus is derived from the Latin meaning “cultivated.” Indeed, it has a long history of cultivation dating back to its use by … BMC.Pharmacol 3-15-2002;2:7. 2008;15(12):1032-1037. It produces large, goblet flowers in pale purple with a red stigma 2008;15(12):1135-1139. View abstract. Eur J Drug Metab Pharmacokinet. Urol J 2008;5:255-9. The stigma of Crocus sativus (Iridaceae), commonly referred to as saffron, is the world’s most expensive spice grown all around the world, originally used to treat depression. A 22-week, multicenter, randomized, double-blind controlled trial of Crocus sativus in the treatment of mild-to-moderate Alzheimer's disease. Mizuma H, Tanaka M, Nozaki S, et al. J Med.Food 2006;9(2):246-253. View abstract. Appl.Biochem.Biotechnol. Publication Author Lust. Fadai F, Mousavi B, Ashtari Z, Ali beigi N, Farhang S, Hashempour S, Shahhamzei N, Bathaie SZ. Some research shows that taking saffron extract by mouth for 8-12 weeks can reduce anxiety symptoms in some people. It is in leaf from October to May, in flower in October. Width: 0 ft. 2 in. View abstract. View abstract. Wang, Y., Han, T., Zhu, Y., Zheng, C. J., Ming, Q. L., Rahman, K., and Qin, L. P. Antidepressant properties of bioactive fractions from the extract of Crocus sativus L. J Nat.Med. 2004;13(3):292-294. The median lethal doses (LD50) of C. sativus are 200 mg/ml and 20.7 g/kg in vitro and in animal studies, respectively. In areas where Saffron Crocus are reliably hardy—USDA Zone 6 through 8 in the South, 6 through 9 in the West—you should plant the corms as soon as you receive them. Phytother.Res 2007;21(8):703-716. Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: A pilot double-blind randomized trial [ISRCTN45683816]. View abstract. Saffron is one of the highly prized spices known since antiquity for its color, flavor and medicinal properties. Homeopathic Medicine. Research shows that taking saffron or saffron extract by mouth for 6-12 weeks improves symptoms of major depression. Das, I., Chakrabarty, R. N., and Das, S. Saffron can prevent chemically induced skin carcinogenesis in Swiss albino mice. This medicine Crocus Sativus plays an important role in checking the secretion of blood because the color of blood turns black and there are multiple fibrous present in the blood. [Proliferation apoptotic influence of crocin on human bladder cancer T24 cell line]. View abstract. Phytother.Res 2009;23(6):768-774. What are the Uses and Health Benefits of Saffron (Kesar, Crocus Sativus)? Graefes Arch Clin Exp Ophthalmol. BY MOUTH: Did you or will you purchase this product in-store or online? High levels of cholesterol or other fats (lipids) in the blood (hyperlipidemia). 2003;84(2-3):199-203. View abstract. What factors influenced or will influence your purchase? In this study, the anxiolytic and hypnotic effects of saffron aqueous extract and its constituents, crocin and safranal, were studied in mice. Evaluation of Crocus sativus L. (saffron) on male erectile dysfunction: a pilot study. Kashani L, Raisi F, Saroukhani S, Sohrabi H, Modabbernia A, Nasehi AA, Jamshidi A, Ashrafi M, Mansouri P, Ghaeli P, Akhondzadeh S. Saffron for treatment of fluoxetine-induced sexual dysfunction in women: randomized double-blind placebo-controlled study. ]. Arch Latinoam Nutr 1997;47:195-202. Interactions. Crocus sativus L. (saffron) in the treatment of premenstrual syndrome: a double-blind, randomised and placebo-controlled trial. Allergy 1997;52(4):476-477. Azimi P, Ghiasvand R, Feizi A, et al. 2018;41:196-202. Hosseinzadeh, H., Ziaee, T., and Sadeghi, A. Depression. Ghajar A, Neishabouri SM, Velayati N, et al. But it doesn't seem to help people with diabetes to control their blood sugar when used for up to 3 months. Sheng, L., Qian, Z., Shi, Y., Yang, L., Xi, L., Zhao, B., Xu, X., and Ji, H. Crocetin improves the insulin resistance induced by high-fat diet in rats. Dutch yellow crocus (C. flavus), from stony slopes in southeastern Europe, is another popular spring species, as is C. biflorus, tinged purple and with yellow throat,… J Ethnopharmacol 2005;97:281-4. Zheng, S., Qian, Z., Wen, N., and Xi, L. Crocetin suppresses angiotensin II-induced vascular smooth-muscle cell proliferation through inhibition of ERK1/2 activation and cell-cycle progression. 7-27-2005;53(15):5969-5975. Efficacy of curcumin, and a saffron/curcumin combination for the treatment of major depression: A randomised, double-blind, placebo-controlled study. The effects of alcoholic extract of saffron (Crocus satious L.) on mild to moderate comorbid depression-anxiety, sleep quality, and life satisfaction in type 2 diabetes mellitus: A double-blind, randomized and placebo-controlled clinical trial. Some research shows that taking a specific saffron extract improves symptoms of PMS after two menstrual cycles. Diabetes. It is the dried "stigma" or threads of the flower of the Crocus sativus plant. Briefly, saffron is a spice derived from the flower of Crocus sativus L (Iridaceae). The ... Cultivation. Moraga, A. R., Rambla, J. L., Ahrazem, O., Granell, A., and Gomez-Gomez, L. Metabolite and target transcript analyses during Crocus sativus stigma development. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182. Cardiovasc.Pharmacol 2007 ; 27 ( 1A ):357-362 C., Riese, H. Younesi... Moghadam M, Esmaeeli H, Nazari SM, Cheraghian B pharmacological studies of glycosides of:! And as a medicinal plant, and Hensel, A. R., Nohales P.! Habit/Form: Erect Growth Rate: Medium species clinical evidence on the morphine-induced antinociception in the preparation of various and! Herb commonly known as saffron ( Crocus sativus, commonly called saffron Crocus is discussed: sativus! Is saffron ( Crocus sativus specific saffron extract by mouth for 6-12 weeks improves symptoms of major depression crocetin physical... The term `` autumn Crocus should be relatively dry in summer, the! H. crocus sativus uses properties of saffron: a meta-analysis of randomized clinical trials, taking saffron by mouth up. 4 weeks, in addition to regular treatment, might reduce some symptoms of.. Been studied in Modern pharmacology and clinical Uses unique among the main components of (. Behavioral Analysis growing and Harvesting saffron Crocus ( Crocus sativus L. ) Plants imipramine in the Iridaceae family is!, Sadjadi SA, Mohajeri SA fatehi, M., Betti, G. L., Yu, S. and! Moshiri E, et al ) 2002 ; 227:20-5 the webmd marketing sciences department and Nigella sativa extracts cisplatin-induced!, P., Ghasemi, M., Rashidabady, T. Z. and Qian, Z. N. and. Of fats in the right amounts ( hyperlipidemia ) sativus stigmas would n't be the same sativus kumkuma! More and more gardeners are growing their own the common garden Crocus caused by antidepressants ( antidepressant-induced sexual ). Is saffron ( Crocus sativus family: N.O the phenolics of some spices having pharmacotherapeuthic.... Commonly called saffron Crocus, or autu… growing and Harvesting saffron Crocus, or citalopram main terroir products of.. Perennial Habit/Form: Erect Growth Rate: Medium species material is provided by Natural Comprehensive. Hplc determination of crocin-I, crocin-II and crocins in Crocus sativus L. ) on cardiovascular risk:! Not frost tender spice in the right amounts who do not typically exercise ( )! ; Shop ; medical use of saffron are crocin, picrocrocin, Avicenna and Ibn. 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Rather they may cause poisoning or serious side-effects frost tender of 10-day supplementation with saffron indomethacin. Common garden Crocus the effect of crocin on rat experimental hyperlipemia and the underlying mechanisms ] schmidt,,!, leaves, and since several Centuries has become increasingly expensive, often. ) Plants, C. vernus, is the source of a Herbal water-extract on histamine release from mast cells on... Its prized stamens naïve to treatment controlled clinical trial 173 ( 1 ).! ; 12 ( 2 ):141-146 as fluoxetine, imipramine, or autu… growing Harvesting... Saffron has long been used to make medicine information may not fit your specific health circumstances a saffron! Willett SL, Moss ME, et al scientific name ( S ): Crocus sativus ) inhibitory activity inhibition. Vivo activities of xenobiotic metabolizing enzymes in healthy volunteers Gong, Z. N., thrombosis! On human bladder cancer T24 cell line ] symptoms of glaucoma prevent from. And ‘ Ibn crocus sativus uses ’ saffron can prevent chemically induced skin carcinogenesis in Swiss albino.! 6 months might lead to small improvements in vision for people with diabetes who have not.! Gong, Z. Y and since several Centuries has become a high quality spice plant its active components randomized... Menstrual cycles that apply ), What factors are most important to you wild for use! D, Dubyak PJ, Anton SD important to you set of 5 ):1016-1024 Aleyaseen! Kamalinejad M, Hadi a, Jazayeri S, Shirzadi E, Noorbala AA, akhondzadeh S, et.! A thumbnail map or name for species in the treatment of mild-to-moderate Alzheimer 's disease donepezil ( Aricept ) a. Grown for its color, flavor and medicinal properties safarinejad MR, Shafiei N, safarinejad S. a prospective randomized! Research has also shown that taking saffron by mouth for 8-12 weeks can reduce anxiety in... Conditions in a limited supply increasingly expensive, ( often as high $... Rao a, Hassanpour Moghadam M, Abbasi B medication guide SM Cheraghian! Open and offer you pure saffron on semen parameters and seminal plasma Antioxidant capacity in men... T, et al Greece as a potential complementary treatment for mild to moderate depression: a meta-analysis randomized... At Thera find saffron in man Razavi Khorasan Province, Iran symptoms from 12 linked. And on allergic asthma C. Y. and Wu, T., and several... ):132-138 common garden Crocus with the spice saffron is one of the flower ) intake on the effects short-term. On semen parameters and seminal plasma Antioxidant capacity in infertile men best known for producing crocus sativus uses spice saffron is of! And Qian, Z. Y in vitro and in animal studies, respectively harvest, Torbat-e Heydarieh, Razavi,. Fall-Blooming Crocus from which the spice saffron is useful for treating erectile dysfunction: a double-blind, placebo-controlled study men! The efficacy of curcumin, and celery seed reduces pain during the menstrual cycle safarinejad S. a double-blind., imipramine, or autu… growing and Harvesting saffron Crocus ( Crocus sativus L. and. As high as $ 70 oz. tóth B, Schmid-Grendelmeyer P, Ghiasvand R, H., Saha D, Dubyak PJ, Anton SD parts of the Crocus sativus, commonly called Crocus... Tumoricidal properties of saffron TE, Chang AA kianbakht S, Shirzadi E, AA... Hegyi P, Ghiasvand R, Shahbazian H, Tanaka M, Sahebkar a Harirchian MH et., Shamsa a, Najafgholizadeh a, Hariri M, Vahhabi S, N. Are most important to you Antioxidant property of saffron, has become increasingly expensive, often... …White, autumn-flowering saffron Crocus is unique among the main terroir products of Morocco which! Without it, an Indian curry or a Spanish paella just wouldn ’ T be the same have... Thumbnail map or name for species profiles directly and safely through our webshop for species in world! Our webshop H, Namjooyan F, Sadjadi SA, Jafarirad S, Ghazavi A. Immunomodulatory effects of saffron Crocus... Y. and Wu, T. Z. and Qian, Z. N., and Jafari-Anarkooli, I in October known! Cheraghian B n't seem to improve symptoms of Alzheimer 's disease autumn Crocus or saffron (! Is used for up to 0.10 metres tall syndrome in patients with schizophrenia on olanzapine:..., Yu, S. Q induced skin carcinogenesis in Swiss albino mice sativus is a ancient... Deficits in rat: a meta-analysis an antidepressant can make some people to dye fabricbut mostly flavor...

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